Factors associated with fetal shunt dislodgement in lower urinary tract obstruction. (8th July 2016)

• Record Type: Journal Article
• Authors: Kurtz, Michael P.; Koh, Chester J.; Jamail, Grace Anne; Sangi‐Haghpeykar, Haleh; Shamshirsaz, Alireza A.; Espinoza, Jimmy; Cass, Darrell L.; Olutoye, Oluyinka O.; Olutoye, Olutoyin A.; Braun, Michael C.; Roth, David R.; Belfort, Michael A.; Ruano, Rodrigo
• Is Part Of: Prenatal diagnosis. Volume 36:Number 8(2016)
• Page Start: 720
• Page End: 725
• Publication Date: 2016-07-08
• Subjects: Prenatal diagnosis -- Periodicals; Fetus -- Diseases -- Diagnosis -- Periodicals; Electronic journals; 618.32075
• DOI: 10.1002/pd.4850
• Languages: English
• ISSNs: 0197-3851

Abstract

Abstract: Objective: To identify factors associated with fetal shunt dislodgement in lower urinary tract obstruction (LUTO). Methods: We conducted a retrospective study of 42 consecutive fetuses with a diagnosis of LUTO in a tertiary fetal center between April 2013 and November 2015. Possible factors associated with prenatal shunt dislodgment were evaluated in fetuses who underwent shunt placement, including gestational age at diagnosis, gestational age at procedure, presence of 'keyhole sign', initial fetal bladder volume and wall thickness, prenatal ultrasonographic renal characteristics, amniotic fluid volume, presence of ascites prior to shunting, and type of fetal shunt. Results: Nineteen (46.3%) fetuses underwent shunt placement at a median gestational age of 19 (range: 16.3–31.1) weeks. Shunt dislodgement occurred in 10 (52.6%) patients. A total of 35 procedures were performed; among which 16 (45.7%) were repeat procedures. The only prenatal factor associated with shunt dislodgement was the type of the shunt; Kaplan–Meier analysis indicated that the Rocket was associated with increased likelihood of remaining orthotopic ( p = 0.04). Conclusion: Fetal shunt dislodgement occurs in approximately half of the patients and appears to be associated with the type of the shunt. Future research is necessary to develop better shunt systems and to investigate different fetal therapeutic approaches. © 2016 John Wiley & Sons, Ltd. Abstract : What's Already Known about this Topic? Shunt dislodgement is the most common technical complication of intervention for fetal LUTO. Predictors of this event are unclear. What does this Study Add? This study explores factors associated with shunt dislodgement in a cohort in which both major shunt types were used. Failure of shunts to remain in the orthotopic position was found to be associated with shunt type.