Front Cover: The Amadori Rearrangement for Carbohydrate Conjugation: Scope and Limitations (Eur. J. Org. Chem. 25/2016). Issue 25 (September 2016)

• Record Type: Journal Article
• Authors: Hojnik, Cornelia; Müller, Anne; Gloe, Tobias‐Elias; Lindhorst, Thisbe K.; Wrodnigg, Tanja M.
• Is Part Of: European journal of organic chemistry. Issue 25(2016)
• Page Start: 4244
• Page End: 4244
• Publication Date: 2016-09
• Subjects: Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201670251
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : The cover picture shows the Amadori rearrangement, which allows the conjugation of carbohydrate moieties to diverse amino components, such as amino acids, lysine‐containing peptides, complex amino‐functionalized glycosides, as well as di‐ and triamines in one step without protecting‐group manipulations. The linkage through a C ‐glycosidic‐type conjugation, which is not sensitive towards enzymatic or chemical hydrolysis in a physiological environment, leads to versatile building blocks for different applications, in particular for biological investigations. Details are discussed in the article by T. K. Lindhorst, T. M. Wrodnigg et al. onp. 4328 ff .