Identifying variations in adherence to the CDC sexually transmitted disease treatment guidelines of Neisseria gonorrhoeae. (July 2016)

• Record Type: Journal Article
• Authors: Boyajian, A.J.; Murray, M.; Tucker, M.; Neu, N.
• Is Part Of: Public health. Volume 136(2016)
• Page Start: 161
• Page End: 165
• Publication Date: 2016-07
• Subjects: Neisseria gonorrhoeae -- Treatment -- Adherence -- STD; Public health -- Periodicals; Public health -- Periodicals; Electronic journals; 362.1
• DOI: 10.1016/j.puhe.2016.04.004
• Languages: English
• ISSNs: 0033-3506

Abstract

Abstract: Objective: Neisseria gonorrhoeae is identified as a national challenge due to emerging antimicrobial resistance. The Centers for Disease Control and Prevention (CDC) sexually transmitted diseases (STD) Treatment guidelines are updated to address emerging concerns. The aims of this study were 1) to determine the proportion of cases that were adherent to two aspects of the treatment guidelines: antimicrobial treatment and follow-up recommendations and 2) to evaluate differences in adherence based on clinical location. Study design: A retrospective review of medical records was performed for the first positive N. gonorrhoeae tests identified in subjects between May 2011 and December 2013 at a large urban academic medical centre. We hypothesised that provider adherence to STD treatment and prevention guidelines was better at STD specialised clinics than non-specialised settings. Methods: Adherence to CDC STD treatment guidelines was determined for both treatment and prevention management. Demographic, testing differences, and appropriate treatment and follow-up between speciality and non-speciality clinics were evaluated using chi-squared, Fisher's exact, and Student's t -test, when appropriate. Results: During the study period, 542/714 positive tests were analysed. Healthcare provider adherence to antimicrobial management guidelines was 82% during the study period. Adherence to the guidelines was 76% and 88% for the 2010 and 2012 time periods, respectively. Non-adherence to recommendations included lack of dual therapy for N. gonorrhoeae in speciality clinics and incorrect dose in non-speciality clinics. Appropriate preventive follow-up was identified in only 31% of cases. Both speciality clinics and non-speciality clinics had errors related to partner therapy. Conclusions: Providers in speciality clinics were more adherent to the guidelines compared with providers at other clinical sites. Significant lack of adherence was identified in the follow-up management of N. gonorrhoeae . Evaluation of treatment errors may help improve medical management of N. gonorrhoeae . Highlights: Clinics specializing in STDs are more adherent to CDC STD treatment guidelines for gonorrhoeae. Errors in adherence to STD treatment guidelines varied by clinic speciality and included errors in antimicrobial agent and follow up. Evaluation and education on changes to STD treatment guidelines for gonorrheal are important.