Impact of psychotic symptoms on cognitive functioning in child and adolescent psychiatric inpatients with severe mood disorders. (30th October 2016)

• Record Type: Journal Article
• Authors: McCarthy, James B.; Weiss, Shira R.; Segovich, Kristin T.; Barbot, Baptiste
• Is Part Of: Psychiatry research. Volume 244(2016)
• Page Start: 223
• Page End: 228
• Publication Date: 2016-10-30
• Subjects: Psychotic symptoms -- Bipolar disorder -- Major depression -- Cognitive functioning -- Mood disorders -- Children and adolescents; Psychiatry -- Periodicals; Psychiatry -- periodicals; Psychiatrie -- Périodiques; 616.89
• DOI: 10.1016/j.psychres.2016.07.049
• Languages: English
• ISSNs: 0165-1781

Abstract

Abstract: Despite established differences in cognitive functioning of adults with mood disorder-related psychosis and those with non-affective psychotic disorders, there is limited evidence of the impact of psychotic symptoms on the cognitive functioning of children and adolescents with mood disorders. This study investigates IQ, working memory, and processing speed scores in 80 child and adolescent inpatients discharged from an intermediate care state psychiatric hospital, using a retrospective chart review. Associations between diagnosis based on DSM-IV criteria (7 with Major Depression- MDD; 43 with Bipolar Disorders-BD, and 30 with Mood Disorders Not Otherwise Specified-NOS), presence of current psychotic features, and cognitive functioning (WISC-IV IQ, Coding, Symbol Search, and Digit Span) were investigated using Multivariate Analyses of Variance. No differences were found in cognitive functioning between patients with MDD and BD, or between those with severe Mood Disorders (MDD or BD) and those with NOS, when controlling for age, gender, and presence of psychotic features. However, patients with severe mood disorders and psychotic features showed lower IQs and greater working memory deficits than those without psychotic features or NOS. Results are discussed in terms of treatment planning for children and adolescents at risk for developing psychotic symptoms and severe mood disorders. Highlights: Exploring cognitive functioning of youth with mood disorders and psychotic symptoms. Study uses a retrospective chart review of 80 child and adolescent inpatients. Severe Mood Disorders (SMD) and psychotic features was associated with lower IQs. SMD and psychotic features was associated with greater working memory weaknesses. Results inform treatment planning and intervention strategies.