The effects of aerobic exercise on cognition in schizophrenia: A 3-month follow-up study. (30th October 2016)

• Record Type: Journal Article
• Authors: Su, Chwen-Yng; Wang, Peng-Wei; Lin, Yi-Jean; Tang, Tze-Chun; Liu, Mei-Fang; Chen, Ming-De
• Is Part Of: Psychiatry research. Volume 244(2016)
• Page Start: 394
• Page End: 402
• Publication Date: 2016-10-30
• Subjects: Exercise -- Neurocognition -- Schizophrenia -- Aerobic fitness; Psychiatry -- Periodicals; Psychiatry -- periodicals; Psychiatrie -- Périodiques; 616.89
• DOI: 10.1016/j.psychres.2016.08.011
• Languages: English
• ISSNs: 0165-1781

Abstract

Abstract: Aerobic exercise (AE) has been shown to improve cognition in patients with schizophrenia. However, it remains unclear whether these exercise-induced cognitive benefits persist beyond the training period. Accordingly, the present study sought to examine the immediate and maintenance effects of AE on a wide range of cognitive functions in 75 schizophrenia patients randomized to 12 weeks of either moderate-intensity treadmill exercise or stretching and toning exercise that served as a control. Participants completed assessments of neurocognition and cardiovascular fitness at pretest, posttest, and 3-month follow-up. The results showed that the AE group outperformed the controls on processing speed and attention at the end of intervention. The two groups did not differ significantly in any cognitive outcome measured at follow-up; however, improvement over time was noted in certain cognitive domains in AE group. The average effect sizes at follow-up were 0.53 and 0.35 for AE and control groups, respectively. There were no significant between-group differences in aerobic fitness at posttest and follow-up, and that fitness level was not related to changes in cognitive performance. These findings provide preliminary evidence for a trend towards beneficial effects of physical activity on cognition over a short follow-up period in favor of AE. Highlights: Processing speed and attention improved after a 3-month aerobic exercise training. Improvement in verbal learning occurred regardless of the type of exercise training. Stretching exercise showed some modest improvements in cognition at follow-up.