A small synthetic molecule functions as a chloride–bicarbonate dual-transporter and induces chloride secretion in cells. Issue 46 (18th May 2016)
- Record Type:
- Journal Article
- Title:
- A small synthetic molecule functions as a chloride–bicarbonate dual-transporter and induces chloride secretion in cells. Issue 46 (18th May 2016)
- Main Title:
- A small synthetic molecule functions as a chloride–bicarbonate dual-transporter and induces chloride secretion in cells
- Authors:
- Liu, Peng-Yun
Li, Shing-To
Shen, Fang-Fang
Ko, Wing-Hung
Yao, Xiao-Qiang
Yang, Dan - Abstract:
- Abstract : A C 2 symmetric small molecule composed ofl -phenylalanine and isophthalamide was found to function as a Cl − /HCO3 − dual transporter and self-assemble into chloride channels. Abstract : A C 2 symmetric small molecule composed ofl -phenylalanine and isophthalamide was found to function as a Cl − /HCO3 − dual transporter and self-assemble into chloride channels. In Ussing-chamber based short-circuit current measurements, this molecule elicited chloride-dependent short-circuit current ( I sc ) increase in both Calu-3 cell and CFBE41o-cell (with F508del mutant CFTR) monolayers.
- Is Part Of:
- Chemical communications. Volume 52:Issue 46(2016)
- Journal:
- Chemical communications
- Issue:
- Volume 52:Issue 46(2016)
- Issue Display:
- Volume 52, Issue 46 (2016)
- Year:
- 2016
- Volume:
- 52
- Issue:
- 46
- Issue Sort Value:
- 2016-0052-0046-0000
- Page Start:
- 7380
- Page End:
- 7383
- Publication Date:
- 2016-05-18
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c6cc01964a ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 1006.xml