A new flavone glycoside from the leaves of Agastache rugosa (Fisch. & C.A.Mey.) Kuntze. (August 2016) - Park, SeonJu
Abstract: Agastache rugosa (Fisch. & C.A.Mey.) Kuntze has been widely used as a food spice and a remedy for colds in Korea, China and Japan. In this study, one new flavone glycoside (1 ) along with six flavonoids (2 –7 ), nine phenyl glycosides (8 –16 ) and three megastigmane glycosides (17 –19 ) were isolated from the leaves of A. rugosa. By extensive spectroscopic methods including 1D and 2D NMR, and MS data, the structure of the new compound (1 ) was elucidated as acacetin 7- O -β-(6″-( E )-crotonylglucopyranoside). From present investigation, compound1 and7 –19 were isolated for the first time from the genus Agastache and1, 16, 18 and19 in the Lamiaceae family. Graphical abstract: Highlights: One new flavone glycoside (1 ) along with eighteen known compounds (2 –19 ) were isolated from Agastache rugosa Kuntze. Compounds1 and7 –19 were isolated for the first time from the genus Agastache . Compounds1, 16, 18 and19 could be potential chemotaxonomic markers for the species.