Sequential detection of multiple phase transitions in model biological membranes using a red-emitting conjugated polyelectrolyte. Issue 18 (21st April 2016)

• Record Type: Journal Article
• Authors: Houston, Judith E.; Kraft, Mario; Scherf, Ullrich; Evans, Rachel C.
• Is Part Of: Physical chemistry chemical physics. Volume 18:Issue 18(2016)
• Page Start: 12423
• Page End: 12427
• Publication Date: 2016-04-21
• Subjects: Chemistry, Physical and theoretical -- Periodicals; 541.3
• DOI: 10.1039/c6cp01553k
• Languages: English
• ISSNs: 1463-9076

Abstract

Abstract : Charge-mediated assembly of an anionic poly(thiophene) leads to a highly sensitive probe of membrane order. Abstract : The anionic conjugated polyelectrolyte, poly[3-(6-sulfothioatehexyl)thiophene] (P3Anionic ), functions as a highly sensitive probe of membrane order, uniquely capable of sequentially detecting the three key phase transitions occurring within model phospholipid bilayers. The observed sensitivity is the result of charge-mediated, selective localisation ofP3Anionic within the head-groups of the phospholipid bilayer.