Non-directed, carbonate-mediated C–H activation and aerobic C–H oxygenation with Cp*Ir catalysts. Issue 24 (16th March 2016)

• Record Type: Journal Article
• Authors: Kerr, M. E.; Ahmed, I.; Gunay, A.; Venditto, N. J.; Zhu, F.; Ison, E. A.; Emmert, M. H.
• Is Part Of: Dalton transactions. Volume 45:Issue 24(2016)
• Page Start: 9942
• Page End: 9947
• Publication Date: 2016-03-16
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/c6dt00234j
• Languages: English
• ISSNs: 1477-9226

Abstract

Abstract : Carbonate additives enhance the activity of [Cp*Ir(H2 O)3 ](OTf)2 for non-directed C–H activations and the aerobic C–H oxygenation of alkyl arenes. Abstract : The effect of oxidatively stable L- and X-type additives on the activity of Cp*Ir catalyst precursors in the C–H activation of arenes has been studied. Turnover numbers for C–H activation of up to 65 can thus be achieved, as determined by H/D exchange in MeOH-D4 . In particular, carbonate additives are found to enhance the C–H activation reactivity of Cp*Ir(H2 O)3 (OTf)2 (1 ) more significantly than L-type ligands investigated in this study. Based on these studies, Cp*Ir/carbonate systems are developed that catalyze the aerobic Csp 3 –H oxygenation of alkyl arenes, employing air as oxidant.