Copper-catalyzed intermolecular amidation of 8-methylquinolines with N-fluoroarylsulfonimides via Csp3–H activation. Issue 21 (11th May 2016)

• Record Type: Journal Article
• Authors: Zhang, Xiaolei; Wu, Rui; Liu, Wanyi; Qian, Dang-Wei; Yang, Jinhui; Jiang, Pengju; Zheng, Qing-Zhong
• Is Part Of: Organic & biomolecular chemistry. Volume 14:Issue 21(2016)
• Page Start: 4789
• Page End: 4793
• Publication Date: 2016-05-11
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c6ob00553e
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : An efficient Cu-catalyzed intermolecular amidation of 8-methylquinolines with N -fluoroarylsulfonimides via Csp 3 –H activation has been developed. Abstract : An efficient copper-catalyzed C–H amidation of 8-methylquinolines with N -fluoroarylsulfonimides via Csp 3 –H activation is described. The reaction proceeds with high functional group tolerance, providing a novel approach to valuable quinolin-8-ylmethanamine derivatives in the absence of an additional oxidant.