First isolation of Candida wangnamkhiaoensis from the blood of immunocompromised paediatric patient. Issue 11 (November 2016)

• Record Type: Journal Article
• Authors: Tap, Ratna Mohd; Ho Betty, Lee Sue; Ramli, Nur Yasmin; Suppiah, Jeyanthi; Hashim, Rohaidah; Sabaratnam, Parameswari; Ginsapu, Stephanie Jane; Gowbei, Annabel; Razak, Mohd Fuat Abd; Sipiczki, Matthias; Ahmad, Norazah
• Is Part Of: Mycoses. Volume 59:Issue 11(2016)
• Page Start: 734
• Page End: 741
• Publication Date: 2016-11
• Subjects: Candida wangnamkhiaoensis -- Hypopichia clade -- fungaemia -- immunocompromised patient; Pathogenic fungi -- Periodicals; Medical mycology -- Periodicals; 616.969
• DOI: 10.1111/myc.12509
• Languages: English
• ISSNs: 0933-7407

Abstract

Summary: Candida wangnamkhiaoensis is a species clustered under the Hyphopichia clade has not ever been isolated from any clinical specimens. To the best of our knowledge, this is the first report of C . wangnamkhiaoensis associated with fungaemia in immunocompromised paediatric patient. The isolate was assigned a strain name as UZ1679/14, in which the identification was confirmed by a polymerase chain reaction‐sequencing of the internal transcribed spacer (ITS) and large subunit (LSU) regions of the rRNA gene. Antifungal susceptibility pattern showed that the isolate was sensitive to anidulafungin, caspofungin, fluconazole and voriconazole. The patient clinically improved after the antifungal treatment with caspofungin.