Ethanolamine: a novel anti-aging agent. (2nd January 2016)

• Record Type: Journal Article
• Authors: Rockenfeller, Patrick; Carmona-Gutierrez, Didac; Pietrocola, Federico; Kroemer, Guido; Madeo, Frank
• Is Part Of: Molecular & cellular oncology. Volume 3:Number 1(2016)
• Publication Date: 2016-01-02
• Subjects: aging -- autophagy -- ethanolamine -- phosphatidylethanolamine -- phosphatidylserine decarboxylase; Tumors -- Periodicals; Neoplasms; Periodicals; 616.99
• DOI: 10.1080/23723556.2015.1019023
• Languages: English
• ISSNs: 2372-3556

Abstract

Abstract : Ethanolamine (Etn) is a naturally occurring aminoalcohol necessary for synthesis of the phospholipid phosphatidylethanolamine (PE), a major component of biological membranes. We recently reported that Etn treatment increases cellular PE levels, thereby inducing cytoprotective autophagy and protecting against aging across species.