Two cases of genital neutrophilic sebaceous adenitis. Issue 10 (5th October 2016)

• Record Type: Journal Article
• Authors: Tohyama, Mikiko; Matsumoto, Keiko; Sayama, Koji
• Is Part Of: Journal of dermatology. Volume 43:Issue 10(2016)
• Page Start: 1221
• Page End: 1223
• Publication Date: 2016-10-05
• Subjects: genital neutrophilic sebaceous adenitis -- menstrual cycle -- minocycline -- recurrent genital herpes -- vulva; Dermatology -- Periodicals; Dermatology -- Japan -- Periodicals; Skin -- Diseases -- Periodicals; 616.5005
• DOI: 10.1111/1346-8138.13448
• Languages: English
• ISSNs: 0385-2407

Abstract

Abstract: Sebaceous glands without a follicular structure are present in the eyelid margin (meibomian glands), lip, glans penis and vulva. Inflammatory disease of a sebaceous gland lacking follicles is rare, except for meibomitis. We report the first two cases of vulval sebaceous adenitis. Painful, yellowish‐orange papules/nodules recurred at the vulval mucocutaneous junction or mucosa during the luteal phase of the menstrual cycle. Histopathologically, a dense neutrophilic infiltration was observed within the sebaceous ducts. In both cases, oral minocycline improved the condition. They had been treated with antiherpetic agents. It is possible that women diagnosed with recurrent genital herpes have genital neutrophilic sebaceous adenitis.