Functional Photoacoustic Imaging of Gastric Acid Secretion Using pH‐Responsive Polyaniline Nanoprobes. Issue 34 (30th June 2016)

• Record Type: Journal Article
• Authors: Li, Junwei; Xiao, Hong; Yoon, Soon Joon; Liu, Chengbo; Matsuura, Drew; Tai, Wanyi; Song, Liang; O'Donnell, Matthew; Cheng, Du; Gao, Xiaohu
• Is Part Of: Small. Volume 12:Issue 34(2016)
• Page Start: 4690
• Page End: 4696
• Publication Date: 2016-06-30
• Subjects: gastric acid secretory assessment -- nanoparticles -- nanoprobes -- photoacoustic imaging -- polyaniline -- stomach imaging; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.201601359
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract : A stomach functional imaging technique based on photoacoustics achieves noninvasive gastric acid secretory assessment utilizing pH‐responsive polyaniline nanoprobes. A testing protocol mimicking clinical practice is established using a mouse model. After imaging, the nanoprobes are excreted outside the body without inducing systematic toxicity. Further optimization and translation of this technology can help alleviate patients' suffering and side effects.