High prevalence of diffuse large B‐cell lymphoma in occult hepatitis B virus‐infected patients in the Tohoku district in Eastern Japan. Issue 12 (6th June 2016)

• Record Type: Journal Article
• Authors: Tajima, Katsushi; Takahashi, Naoto; Ishizawa, Kenichi; Murai, Kazunori; Akagi, Tomoaki; Noji, Hideyoshi; Sasaki, Osamu; Wano, Masaharu; Itoh, Jugoh; Kato, Yuichi; Scichishima, Tsutomu; Ishida, Yoji; Harigae, Hideo; Sawada, Kenichi
• Is Part Of: Journal of medical virology. Volume 88:Issue 12(2016)
• Page Start: 2206
• Page End: 2210
• Publication Date: 2016-06-06
• Subjects: clinicopathologic features -- diffuse large B‐cell lymphoma -- hepatitis B virus -- malignant lymphoma -- occult HBV infection; Virology -- Periodicals; 616
• DOI: 10.1002/jmv.24584
• Languages: English
• ISSNs: 0146-6615

Abstract

Abstract : Occult hepatitis B virus (HBV) infection is a clinical challenge, but its relationship to clinicopathologic features and the risk of progression to malignant lymphoma (ML) are poorly defined. We estimated the prevalence of HBV infection of 1, 358 patients with newly diagnosed ML. HBV infection was more prevalent in ML than in control patients. The occult HBV infection group had a higher median onset age, no liver or spleen involvement, and higher prevalence of diffuse large B‐cell lymphoma than the other groups, indicating that occult HBV infection is a distinct clinicopathologic entity. J. Med. Virol. 88:2206–2210, 2016 . © 2016 Wiley Periodicals, Inc.