Metal–Organic‐Framework‐Derived Mesoporous Carbon Nanospheres Containing Porphyrin‐Like Metal Centers for Conformal Phototherapy. Issue 38 (27th July 2016)

• Record Type: Journal Article
• Authors: Wang, Shunhao; Shang, Lu; Li, Linlin; Yu, Yingjie; Chi, Chongwei; Wang, Kun; Zhang, Jie; Shi, Run; Shen, Heyun; Waterhouse, Geoffrey I. N.; Liu, Sijin; Tian, Jie; Zhang, Tierui; Liu, Huiyu
• Is Part Of: Advanced materials. Volume 28:Issue 38(2016)
• Page Start: 8379
• Page End: 8387
• Publication Date: 2016-07-27
• Subjects: mesoporous carbon nanoframes -- photodynamic therapy -- photothermal therapy -- porphyrin‐like metal centers -- reactive oxygen species; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201602197
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : Mesoporous carbon nanospheres containing porphyrin‐like metal centers (denoted as "PMCS") are successfully synthesized by the pyrolysis of an imidazolate framework using a mesoporous‐silica protection strategy. The PMCS allow infrared and photoacoustic imaging and synergetic photothermal therapy/photodynamic therapy derived from the porphyrin‐like moieties, offering the possibility of real‐time monitoring of therapeutic processes and image‐guided precise conformal phototherapy. PMCS thus represent a novel multifunctional theranostic platform for improved treatment efficiencies.