Spiro-condensation of 5-methoxycarbonyl-1H-pyrrole-2, 3-diones with cyclic enoles to form spiro substituted furo[3, 2-c]-coumarins and quinolines. Issue 88 (6th September 2016)

• Record Type: Journal Article
• Authors: Dubovtsev, Alexey Yu.; Silaichev, Pavel S.; Nazarov, Mikhail A.; Dmitriev, Maksim V.; Maslivets, Andrey N.; Rubin, Michael
• Is Part Of: RSC advances. Volume 6:Issue 88(2016)
• Page Start: 84730
• Page End: 84737
• Publication Date: 2016-09-06
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra16889b
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : Highly efficient spiro-cyclization enabling cyclic enoles to act as 1, 3-bis-nucleophiles in reaction with pyrrole-2, 3-diones acting as 1, 2-bis-electrophiles was developed. Abstract : Highly efficient spiro-condensation enabling cyclic enoles to act as 1, 3-bis-nucleophiles in reaction with pyrrole-2, 3-diones acting as 1, 2-bis-electrophiles was developed. The corresponding furo[3, 2- c ]coumarins and furo[3, 2- c ]quinolines containing a spiro pyrrole fragment were obtained in high yields.