Aggregation induced emission controlled by a temperature-sensitive organic–inorganic hybrid polymer with a particular LCST. Issue 89 (9th September 2016)

• Record Type: Journal Article
• Authors: Li, Mengmeng; Song, Xiaoyan; Zhang, Tingbin; Zeng, Lintao; Xing, Jinfeng
• Is Part Of: RSC advances. Volume 6:Issue 89(2016)
• Page Start: 86012
• Page End: 86018
• Publication Date: 2016-09-09
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra16244d
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : The fluorescence intensity change of TPE encapsulated in POSS–PNIPAM with a particular LCST (37.5 °C) with the temperature change. Abstract : In this study, an organic–inorganic temperature-sensitive polymer encapsulating tetraphenylethene (TPE) was designed. Its fluorescence intensity is sensitive to temperature changes and reaches a maximum at normal cell temperature. Firstly, the organic–inorganic hybrid polymer, polyhedral oligomeric silsesquioxane-based-poly( N -isopropylacrylamide) (POSS- b -PNIPAM) with a particular LCST of 37.5 °C, was synthesized by atom transfer radical polymerization. POSS- b -PNIPAM self-assembled in aqueous solutions to form stable micelles and then TPE was assembled into the micelles in water. The fluorescence intensity of TPE encapsulated in POSS- b -PNIPAM can be tuned by changing the temperature. The fluorescence intensity of TPE encapsulated in POSS- b -PNIPAM reached a maximum at 37 °C, which is much higher than the TPE fluorescence intensity at the same temperature. TPE encapsulated in POSS- b -PNIPAM still showed high fluorescence intensity after entering HeLa cells at 37 °C.