Synthesis, crystal structures, and DNA-binding studies of two silver(I) complexes with 1, 3-bis(1-ethylbenzimidazol-2-yl)-2-thiapropane. Issue 19 (1st October 2016)

• Record Type: Journal Article
• Authors: Xu, Yuling; Wu, Huilu; Zhang, Han; Aderinto, Stephen Opeyemi; Yang, Zaihui
• Is Part Of: Journal of coordination chemistry. Volume 69:Issue 19(2016)
• Page Start: 2988
• Page End: 2998
• Publication Date: 2016-10-01
• Subjects: Benzimidazole -- silver(I) complex -- crystal structure -- DNA-binding property -- synthesis; Coordination compounds -- Periodicals; 541.2242
• DOI: 10.1080/00958972.2016.1218484
• Languages: English
• ISSNs: 0095-8972

Abstract

Abstract: Two new silver(I) complexes, [Ag(bebt)(methacrylate)] (1 ) and [Ag2 (bebt)2 ](pic)2 (2 ) (bebt = 1, 3-bis(1-ethylbenzimidazol-2-yl)-2-thiapropane, pic = picrate), have been synthesized and characterized by physico-chemical and spectroscopic methods. Single-crystal X-ray diffraction revealed that the structure of1 was four-coordinate in a distorted tetrahedral geometry, while in2, it may be described as a 2 + 1 coordinated silver(I) compound with a nearly linear N–Ag–N backbone and a weak Ag–S interaction. Two ligands are arranged in a face-to-face syn conformation to coordinate to two Ag(I) ions from opposite directions in2, generating a U-type double layer structure around the metal ions. Experimental studies of the DNA-binding properties indicated that free bebt and both complexes bind to DNA via intercalation, and the order of the binding affinity is2 > 1 > bebt. Abstract :