Supercritical carbon dioxide extraction of astaxanthin from Paracoccus NBRC 101723: Mathematical modelling study. Issue 13 (1st September 2016)

• Record Type: Journal Article
• Authors: Chougle, Jyoti A.; Bankar, Sandip B.; Chavan, Prakash V.; Patravale, Vandana B.; Singhal, Rekha S.
• Is Part Of: Separation science and technology. Volume 51:Issue 13(2016)
• Page Start: 2164
• Page End: 2173
• Publication Date: 2016-09-01
• Subjects: Astaxanthin -- entrainer -- mathematical modelling -- solubility parameter -- supercritical extraction; Separation (Technology) -- Periodicals; 660.284205
• DOI: 10.1080/01496395.2016.1178288
• Languages: English
• ISSNs: 0149-6395

Abstract

ABSTRACT: Astaxanthin (AX) is a secondary metabolite that accumulates inside the cell during Paracoccus fermentation. The fermentation biomass was extracted using supercritical carbon dioxide (SC-CO2 ). The solubility parameter of AX, CO2 and entrainer solvents was calculated and validated with experimental results. The pressure and particle size of the biomass had a significant effect on the extraction of AX. A maximum recovery of 963.33 μg/g of AX was obtained after SC-CO2 extraction at 40ºC, 350 bar and a run time of 60 min with ethanol (20% v/w) as an entrainer. Further, the experimental data has been modelled using non-linear regression analysis method.