Comparison of the Utility and Validity of Three Scoring Tools to Measure Skin Involvement in Patients With Juvenile Dermatomyositis. Issue 10 (16th September 2016)

• Record Type: Journal Article
• Authors: Campanilho‐Marques, Raquel; Almeida, Beverley; Deakin, Claire; Arnold, Katie; Gallot, Natacha; de Iorio, Maria; Nistala, Kiran; Pilkington, Clarissa A.; Wedderburn, Lucy R.
• Other Names: Armon Kate investigator.; Ellis‐Gage Joe investigator.; Roper Holly investigator.; Briggs Vanja investigator.; Watts Joanna investigator.; McCann Liza investigator.; Roberts Ian investigator.; Baildam Eileen investigator.; Hanna Louise investigator.; Lloyd Olivia investigator.; Riley Phil investigator.; McGovern Ann investigator.; Ryder Clive investigator.; Scott Janis investigator.; Thomas Beverley investigator.; Southwood Taunton investigator.; Al‐Abadi Eslam investigator.; Wyatt Sue investigator.; Jackson Gillian investigator.; Amin Tania investigator.; Wood Mark investigator.; VanRooyen Vanessa investigator.; Burton Deborah investigator.; Davidson Joyce investigator.; Gardner‐Medwin Janet investigator.; Martin Neil investigator.; Ferguson Sue investigator.; Waxman Liz investigator.; Browne Michael investigator.; Friswell Mark investigator.; Foster Helen investigator.; Swift Alison investigator.; Jandial Sharmila investigator.; Stevenson Vicky investigator.; Wade Debbie investigator.; Sen Ethan investigator.; Smith Eve investigator.; Qiao Lisa investigator.; Watson Stuart investigator.; Venning Helen investigator.; Satyapal Rangaraj investigator.; Stretton Elizabeth investigator.; Jordan Mary investigator.; Mosley Ellen investigator.; Frost Anna investigator.; Crate Lindsay investigator.; Warrier Kishore investigator.; Wedderburn Lucy investigator.; Pilkington Clarissa investigator.; Hasson Nathan investigator.; Nistala Kiran investigator.; Maillard Sue investigator.; Halkon Elizabeth investigator.; Brown Virginia investigator.; Juggins Audrey investigator.; Smith Sally investigator.; Lunt Sian investigator.; Enayat Elli investigator.; Varsani Hemlata investigator.; Kassoumeri Laura investigator.; Beard Laura investigator.; Arnold Katie investigator.; Glackin Yvonne investigator.; Simou Stephanie investigator.; Campanilho‐Marques Raquel investigator.; Almeida Beverley investigator.; Murray Kevin investigator.; Ioannou John investigator.; Suffield Linda investigator.; Al‐Obaidi Muthana investigator.; Lee Helen investigator.; Leach Sam investigator.; Smith Helen investigator.; Wilkinson Nick investigator.; Inness Emma investigator.; Kendall Eunice investigator.; Mayers David investigator.; Clinch Jacqui investigator.; Pluess‐Hall Helen investigator.;
• Is Part Of: Arthritis care & research. Volume 68:Issue 10(2016:Oct.)
• Page Start: 1514
• Page End: 1521
• Publication Date: 2016-09-16
• Subjects: Arthritis -- Periodicals; Rheumatism -- Periodicals; 616.72
• DOI: 10.1002/acr.22867
• Languages: English
• ISSNs: 2151-464X

Abstract

Abstract : Objective: To compare the abbreviated Cutaneous Assessment Tool (CAT), Disease Activity Score (DAS), and Myositis Intention to Treat Activity Index (MITAX) and correlate them with the physician's 10‐cm skin visual analog scale (VAS) in order to define which tool best assesses skin disease in patients with juvenile dermatomyositis. Methods: A total of 71 patients recruited to the UK Juvenile Dermatomyositis Cohort and Biomarker Study were included and assessed for skin disease using the CAT, DAS, MITAX, and skin VAS. The Childhood Myositis Assessment Scale (CMAS), manual muscle testing of 8 groups (MMT8), muscle enzymes, inflammatory markers, and physician's global VAS were recorded. Relationships were evaluated using Spearman's correlations and predictors with linear regression. Interrater reliability was assessed using intraclass correlation coefficients. Results: All 3 tools showed correlation with the physician's global VAS and skin VAS, with DAS skin showing the strongest correlation with skin VAS. DAS skin and CAT activity were inversely correlated with CMAS and MMT8, but these correlations were moderate. No correlations were found between the skin tools and inflammatory markers or muscle enzymes. DAS skin and CAT were the quickest to complete (mean ± SD 0.68 ± 0.1 minutes and 0.63 ± 0.1 minutes, respectively). Conclusion: The 3 skin tools were quick and easy to use. The DAS skin correlated best with the skin VAS. The addition of CAT in a bivariate model containing the physician's global VAS was a statistically significant estimator of skin VAS score. We propose that there is scope for a new skin tool to be devised and tested, which takes into account the strengths of the 3 existing tools.