Extensive Postradiation Ocular and Diffuse Cranial Neuromyotonia Mimicking Myasthenia Gravis. Issue 5 (September 2016)

• Record Type: Journal Article
• Authors: Hardy, Todd A.; Lee, Andrew W.; Yiannikas, Con; Chen, Celia S.; Reddel, Stephen W.
• Is Part Of: Neurologist. Volume 21:Issue 5(2016)
• Publication Date: 2016-09
• Subjects: radiotherapy -- EMG -- ptosis -- hyperexcitability -- video -- fourth ventricle glioma -- complex ophthalmoplegia -- neurophysiology; Nervous System Diseases -- Periodicals; Nervous system -- Diseases -- Periodicals; Neurologie; 616.8
• DOI: 10.1097/NRL.0000000000000088
• Languages: English
• ISSNs: 1074-7931

Abstract

Abstract : Background: Ocular neuromyotonia is a rare, but well-recognized, complication of cranial irradiation. Case Report: Using figures and videos, we report a 52-year-old man with extensive ocular, brainstem, and lower cranial nerve neuromyotonia postradiation therapy for a fourth ventricle glioma who, in the context of an apparently positive edrophonium test, was initially misdiagnosed with myasthenia gravis. Conclusions: This is the first case of postirradiation neuromyotonia to be reported with such extensive cranial nerve and brainstem involvement. Abstract : Supplemental Digital Content is available in the text.