Thalidomide induces mucosal healing in postoperative Crohn disease endoscopic recurrence: Case report and literature review. Issue 36 (September 2016)

• Record Type: Journal Article
• Authors: Hu, Huiqin; Wang, Xinying; Liu, Side
• Other Names: Scalisi. Giuseppe section editor.
• Is Part Of: Medicine. Volume 95:Issue 36(2016)
• Publication Date: 2016-09
• Subjects: case report -- Crohn disease -- mucosal healing -- postoperative endoscopic recurrence -- thalidomide; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000004799
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Background: Thalidomide has been successful use in patients with refractory Crohn disease (CD) in recent years. Methods: We collected the data of a postoperative CD patient who was prescribed thalidomide to induce remission and reviewed the relevant literatures. Results: A 51-year-old female was diagnosed as CD after an urgent terminal intestinal resection and presented endoscopic recurrence despite the prophylactic treatment with azathioprine (AZA). Fortunately, she achieved mucosal healing (MH) at a low dose of thalidomide for 15 months. Conclusion: Thalidomide is effective to induce MH in the postoperative CD endoscopic recurrence.