Infections on the rise: Raoultella spp., clinical and microbiological findings from a retrospective study, 2010–2014. Issue 1 (2nd January 2016)

• Record Type: Journal Article
• Authors: Boattini, Matteo; Almeida, André; Cardoso, Catarina; Cruz, Cristiano Silva; Machado, Catarina; Vesza, Zsófia; Tosatto, Valentina; Maia, Dionísio; Cardoso, Sara; Pinto, Margarida; Moura, Rita Barata; Garcia, Teresa; Guerreiro, António Sousa
• Is Part Of: Infectious diseases. Volume 48:Issue 1(2016:Jan.)
• Page Start: 87
• Page End: 91
• Publication Date: 2016-01-02
• Subjects: Raoultella -- Enterobacteriaceae -- gram-negative -- multiple drug resistance -- infection; Communicable diseases -- Periodicals; Communicable Diseases -- Periodicals; Communicable diseases; Periodicals; 616.9
• DOI: 10.3109/23744235.2015.1082619
• Languages: English
• ISSNs: 2374-4235

Abstract

Abstract : We performed a retrospective analysis of clinical and laboratory data over 5 years in a tertiary centre to assess clinical and microbiological characteristics of patients with Raoultella spp. infection. Raoultella spp. were deemed responsible for clinical infections in 57 patients ( R. planticola, n = 32 and R. ornithinolytica, n = 25). The most prevalent diagnoses for R. planticola were cystitis (50%; n = 16) followed by bacteraemia and pneumonia (9.4%; n = 3); for R. ornithinolytica, cystitis (36%; n = 9) followed by pneumonia (24%; n = 6). Immunodeficiency was present in 18 patients (56.3%) with R. planticola and in 16 patients (64%) with R. ornithinolytica infection. Of these, 55.6% and 37.5% had diabetes and 27.8% and 18.% were solid organ transplant recipients, respectively. All isolates were sensitive to third-generation cephalosporins, fluoroquinolones and aminoglycosides. Mortality of infections with R. planticola ( n = 5; 15.6%) was higher than for R. ornithinolytica ( n = 2; 8.0%), but the difference was not statistically significant.