A new sesquiterpene from the gorgonian coral Menella sp. Issue 20 (17th October 2016)

• Record Type: Journal Article
• Authors: Peng, Qi; Liu, Fen; Sun, Huan; Liao, Xiao-Jian; Feng, Mei-Ran; Liu, Ting-Ting; Xu, Zheng-Xiong; Zhang, Jun; Xu, Shi-Hai
• Is Part Of: Natural product research. Volume 30:Issue 20(2016)
• Page Start: 2299
• Page End: 2304
• Publication Date: 2016-10-17
• Subjects: Gorgonian coral -- Menella sp. -- sesquiterpene -- cytotoxicity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2016.1166496
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: A new sesquiterpene named menecubebane B (1) and a known analogue (2) were isolated from the gorgonian coral Menella sp. Their structures were elucidated by the extensive analyses of spectroscopic data and by the comparison with related literature. Cytotoxic effect against both Eca9706 and HeLa cell lines was evaluated, revealing 1 exhibited moderate cytotoxicity against the two cell lines involved with IC50 values being 20.8 and 30.6 μM, respectively. Abstract :