A new fatty acid ester from an edible mushroom Rhizopogon luteolus. Issue 20 (17th October 2016)

• Record Type: Journal Article
• Authors: Tel-Çayan, Gülsen; Muhammad, Akhtar; Duru, Mehmet Emin; Öztürk, Mehmet; Adhikari, Achyut; Türkoğlu, Aziz
• Is Part Of: Natural product research. Volume 30:Issue 20(2016)
• Page Start: 2258
• Page End: 2264
• Publication Date: 2016-10-17
• Subjects: Rhizopogon luteolus -- fatty acid -- ergosterol -- phenolic compounds -- antioxidant activity -- anticholinesterase activity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2016.1160237
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Phytochemical investigation of the Rhizopogon luteolus Fr. led to the isolation of one new fatty acid ester, 3-hydroxy-2, 4-dimethylheptacosyl acetate (1 ) together with two known compounds tetracosanoic acid (2 ) and ergosterol (3 ). 1D and 2D NMR, and MS techniques were used for structural elucidation. Phenolic and fatty acid compositions were identified using HPLC–DAD and GC–MSD, respectively. Fumaric acid was the major phenolic acid, whereas linoleic, stearic and oleic acids were the most abundant fatty acids. Antioxidant and anticholinesterase activities of the extracts and compounds (1 –3 ) were tested spectrophotometrically. Among the extracts, hexane extract showed the highest activity in all tests, particularly in β-carotene-linoleic acid assay (IC50 : 16.65 ± 1.12 μg/mL). Furthermore, compound3 exhibited higher antioxidant and anticholinesterase activities. The study indicates that R. luteolus can be used in food, cosmetic and pharmaceutical industries. Abstract :