Microwave-assisted neat synthesis of α-aminophosphonate/phosphinate derivatives of 2-(2-aminophenyl)benzothiazole as potent antimicrobial and antioxidant agents. (2nd October 2016)

• Record Type: Journal Article
• Authors: Thaslim Basha, Shaik; Sudhamani, Hasti; Rasheed, Syed; Venkateswarlu, Nagam; Vijaya, Tartte; Naga Raju, Chamarthi
• Is Part Of: Phosphorus, sulfur, and silicon and the related elements. Volume 191:Number 10(2016)
• Page Start: 1339
• Page End: 1343
• Publication Date: 2016-10-02
• Subjects: 2-(2-Aminophenyl) benzothiazole -- neat conditions -- microwave irradiation -- Kabachnik-Fields reaction -- antimicrobial and antioxidant activity; Sulfur compounds -- Periodicals; Organosulfur compounds -- Periodicals; Phosphorus compounds -- Periodicals; Organophosphorus compounds -- Periodicals; Silicon compounds -- Periodicals; Organosilicon compounds -- Periodicals; 546
• DOI: 10.1080/10426507.2016.1192629
• Languages: English
• ISSNs: 1042-6507

Abstract

GRAPHICAL ABSTRACT: ABSTRACT: A series of diethyl/ethylphenyl {2-(benzo[ d ]thiazol-2-yl)phenylamino}phosphonates and phosphinates were synthesized under microwave irradiation and neat conditions via Kabachnik-Fields reaction in high yields (80%–93%). The compounds were screened for antimicrobial and antioxidant properties. A few compounds showed effective antibacterial and antifungal activities at MIC value 12.5 μg/mL as compared with the standard at MIC value 6.25 μg/mL.