Prognostic Significance of the Preoperative Lymphocyte to Monocyte Ratio in Patients With Stage I Non-Small Cell Lung Cancer Undergoing Complete Resection. (13th September 2016)

• Record Type: Journal Article
• Authors: Xia, Honggang; Sun, Zhongyi; Deng, Limin; Zhu, Deqing; Wang, Dongbin
• Is Part Of: Cancer investigation. Volume 34:Number 8(2016)
• Page Start: 378
• Page End: 384
• Publication Date: 2016-09-13
• Subjects: Lymphocyte to monocyte ratio -- non-small cell lung cancer -- prognosis; Cancer -- Periodicals; Oncology -- Periodicals; Medical Oncology -- Periodicals; Neoplasms -- Periodicals; 616.994
• DOI: 10.1080/07357907.2016.1213276
• Languages: English
• ISSNs: 0735-7907

Abstract

ABSTRACT: In this study, we investigated the correlation between lymphocyte to monocyte ratio (LMR) and clinical outcomes in stage I non-small cell lung cancer (NSCLC) patients. A total of 439 stage I NSCLC patients were enrolled in this study. Multivariate analyses identified LMR as an independent prognostic factor for recurrence-free survival and overall survival (hazard ratio (HR: 0.469, 95% Confidence Interval (CI): 0.325–0.677, and p < 0.001, and HR: 0.478, 95% CI: 0.332–0.688, and p < 0.001; respectively). Compared with the high LMR group, the proportion of patients who developed distant metastasis was significantly higher in the low LMR group.