Sulfonic acid–functionalized Wang resin (Wang-OSO3H) as polymeric acidic catalyst for the ecofriendly multicomponent synthesis of polyhydroquinolines via Hantzsch condensation. Issue 18 (16th September 2016)

• Record Type: Journal Article
• Authors: Dhanunjaya Rao, A. V.; Surasani, Rajendra; Vykunteswararao, B. P.; Bhaskarkumar, T.; Srikanth, B.; Jogdand, Nivrutti R.; Kalita, Dipak; Lilakar, Jaydeep Kumar D.; Siddaiah, Vidavalur; Sanasi, Paul Douglas; Raghunadh, Akula
• Is Part Of: Synthetic communications. Volume 46:Issue 18(2016)
• Page Start: 1519
• Page End: 1528
• Publication Date: 2016-09-16
• Subjects: Green chemistry -- Hantzsch condensation -- polyhydroquinoline derivatives -- reusable catalyst -- Wang-OSO3H -- water; Organic compounds -- Synthesis -- Periodicals; Chemistry, Organic; Synthesis; 547.205
• DOI: 10.1080/00397911.2016.1213850
• Languages: English
• ISSNs: 0039-7911

Abstract

ABSTRACT: An efficient and green approach has been developed for the synthesis of polyhydroquinoline derivatives via Hantzsch condensation reaction directly from corresponding substituted aromatic and aliphatic aldehydes, β -keto compounds, active methylene compounds, and ammonium chloride using recyclable polymer-supported sulfonic acid catalyst under aqueous conditions. Environmental acceptability, operational simplicity, low cost, excellent functional group compatibility, and high yields are the important features of this protocol. GRAPHICAL ABSTRACT: