Polyacrylamide backbones for polyvalent bioconjugates using "post-click" chemistry. Issue 38 (1st August 2016)

• Record Type: Journal Article
• Authors: Nagao, M.; Kurebayashi, Y.; Seto, H.; Takahashi, T.; Suzuki, T.; Hoshino, Y.; Miura, Y.
• Is Part Of: Polymer chemistry. Volume 7:Issue 38(2016)
• Page Start: 5920
• Page End: 5924
• Publication Date: 2016-08-01
• Subjects: Polymers -- Periodicals; Macromolecules -- Periodicals; Polymerization -- Periodicals; 547.705
• DOI: 10.1039/c6py00904b
• Languages: English
• ISSNs: 1759-9954

Abstract

Abstract : This paper reports the synthesis and application of acrylamide-type neoglycoconjugates interacting with practical targets. Abstract : This paper reports the synthesis and application of acrylamide-type neoglycoconjugates interacting with practical targets. Polymer backbones with acrylamide and acrylamide derivatives bearing alkyne groups were prepared using living radical polymerization. Oligosaccharides were introduced into the backbones using copper-catalysed azide–alkyne cycloaddition "post-click" chemistry.