Hepatoprotective phenylethanoid glycosides from Cirsium setosum. Issue 16 (17th August 2016)

• Record Type: Journal Article
• Authors: Ma, Qinge; Guo, Yongming; Luo, Baomin; Liu, Wenmin; Wei, Rongrui; Yang, Chunxia; Ding, Chenghua; Xu, Xuefeng; He, Minghui
• Is Part Of: Natural product research. Volume 30:Issue 16(2016)
• Page Start: 1824
• Page End: 1829
• Publication Date: 2016-08-17
• Subjects: Cirsium setosum -- phenylethanoid glycoside -- hepatoprotective activity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2015.1084304
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Two new phenylethanoid glycosides, namely β -D-glucopyranoside, 1″- O -(7 S )-7-(3-methoxyl-4-hydroxyphenyl)-7-methoxyethyl-3″- α -L-rhamnopyranosyl-4″-[(8 E )-7-(3-methoxyl-4-hydroxyphenyl)-8-propenoate] (1 ) and β -D-glucopyranoside, 1″- O -(7 S )-7-(3-methoxyl-4-hydroxyphenyl)-7-methoxyethyl-3″- α -L-rhamnopyranosyl-4″-[(8 E )-7-(4-hydroxyphenyl)-8-propenoate] (2 ), together with six phenylethanoid glycosides were isolated from Cirsium setosum . Their structures were elucidated by their spectroscopic data and references. Compounds2, 4, 5, 7 and8 (10 μM) exhibited moderate hepatoprotective activities. Compounds (3–8 ) were obtained from this plant for the first time. Abstract :