3D Bioprinting: Biologically Inspired Smart Release System Based on 3D Bioprinted Perfused Scaffold for Vascularized Tissue Regeneration (Adv. Sci. 8/2016). Issue 8 (August 2016)

• Record Type: Journal Article
• Authors: Cui, Haitao; Zhu, Wei; Holmes, Benjamin; Zhang, Lijie Grace
• Is Part Of: Advanced science. Volume 3:Issue 8(2016:Aug.)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2016-08
• Subjects: 3D bioprinting -- biologically inspired smart release -- nanocoating -- spatiotemporal coordination -- vascularized bone regeneration; Science -- Periodicals; 505
• DOI: 10.1002/advs.201670043
• Languages: English
• ISSNs: 2198-3844

Abstract

Abstract : In the article 1600058, Lijie Grace Zhang and co‐workers develop a comprehensive design of engineered vascularized bone construct (top image), integrating biomimetic 3D printed fluid perfused microstructure with a biologically inspired smart growth factor release system (colored fibers). The design provides great potential for complex tissue/organ regeneration by delivering multiple growth factors (small spheres), in a highly coordinated manner based on appropriate time, location and biological signal.