Chemo‐ and Regioselective Rhodium(I)‐Catalyzed [2+2+2] Cycloaddition of Allenynes with Alkynes. Issue 34 (20th July 2016)

• Record Type: Journal Article
• Authors: Yasuda, Shigeo; Kawaguchi, Yasuaki; Okamoto, Yuta; Mukai, Chisato
• Is Part Of: Chemistry. Volume 22:Issue 34(2016)
• Page Start: 12181
• Page End: 12188
• Publication Date: 2016-07-20
• Subjects: alkynes -- allenes -- cycloaddition -- regioselectivity -- rhodium; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201602239
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract: A highly chemo‐ and regioselective partially intramolecular rhodium(I)‐catalyzed [2+2+2] cycloaddition of allenynes with alkynes is described. A range of diverse polysubstituted benzene derivatives could be synthesized in good to excellent yields, in which the allenynes served as synthetic equivalent to the diynes. A high regioselectivity could be observed when allenynes were treated with unsymmetrical alkynes. Abstract : Under control : A highly chemo‐ and regioselective partially intramolecular rhodium(I)‐catalyzed [2+2+2] cycloaddition of allenynes with alkynes is described (see scheme). A range of diverse polysubstituted benzene derivatives could be synthesized in good to excellent yields, in which the allenynes served as synthetic equivalent to the diynes. A high regioselectivity could be observed when allenynes were treated with unsymmetrical alkynes.