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ChemInform Abstract: Lewis Base Catalyzed Trialkylsilylcyanide Additions to Cyclic 2‐Fluoroketones: Nucleophile Directed Access to Both cis‐ and trans‐Stereoisomers. Issue 36 (August 2016)
Record Type:
Journal Article
Title:
ChemInform Abstract: Lewis Base Catalyzed Trialkylsilylcyanide Additions to Cyclic 2‐Fluoroketones: Nucleophile Directed Access to Both cis‐ and trans‐Stereoisomers. Issue 36 (August 2016)
Main Title:
ChemInform Abstract: Lewis Base Catalyzed Trialkylsilylcyanide Additions to Cyclic 2‐Fluoroketones: Nucleophile Directed Access to Both cis‐ and trans‐Stereoisomers.
Abstract: Cyclic 2‐fluoroketones react with cyanide (II) and iPr2 NEt as the catalyst to give cis‐addition product predominantly, whereas methoxide catalyzed reactions with cyanide (V) favour the formation of trans‐addition products.