A Copper‐Catalyzed Decarboxylative Amination/Hydroamination Sequence: Switchable Synthesis of Functionalized Indoles. (4th September 2016)
- Record Type:
- Journal Article
- Title:
- A Copper‐Catalyzed Decarboxylative Amination/Hydroamination Sequence: Switchable Synthesis of Functionalized Indoles. (4th September 2016)
- Main Title:
- A Copper‐Catalyzed Decarboxylative Amination/Hydroamination Sequence: Switchable Synthesis of Functionalized Indoles
- Authors:
- Li, Tian‐Ren
Cheng, Bei‐Yi
Wang, Ya‐Ni
Zhang, Mao‐Mao
Lu, Liang‐Qiu
Xiao, Wen‐Jing - Abstract:
- Abstract: A copper‐catalyzed decarboxylative amination/hydroamination sequence of propargylic carbamates with various nucleophiles is described for the first time. It features an earth‐abundant metal catalyst, mild reaction conditions, and high efficiency. Further treatments of the resultant key intermediates using an acid or a base in one pot enable the controllable and divergent synthesis of two types of functionalized indoles. Moreover, experiments to demonstrate the synthetic potential of this methodology are performed.
- Is Part Of:
- Angewandte Chemie. Volume 128:Number 40(2016)
- Journal:
- Angewandte Chemie
- Issue:
- Volume 128:Number 40(2016)
- Issue Display:
- Volume 128, Issue 40 (2016)
- Year:
- 2016
- Volume:
- 128
- Issue:
- 40
- Issue Sort Value:
- 2016-0128-0040-0000
- Page Start:
- 12610
- Page End:
- 12614
- Publication Date:
- 2016-09-04
- Subjects:
- Alkine -- Hydroaminierungen -- Indole -- Kupfer -- Synthesemethoden
Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/ange.201605900 ↗
- Languages:
- English
- ISSNs:
- 0044-8249
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 64.xml