Design and Synthesis of Novel EGFR Inhibitors with L‐Rhamnose–Benzoxazinone Hybrids. (9th October 2015)
- Record Type:
- Journal Article
- Title:
- Design and Synthesis of Novel EGFR Inhibitors with L‐Rhamnose–Benzoxazinone Hybrids. (9th October 2015)
- Main Title:
- Design and Synthesis of Novel EGFR Inhibitors with L‐Rhamnose–Benzoxazinone Hybrids
- Authors:
- Zhang, Renshuai
Chen, Shaopeng
Wu, Guanzhao
Wan, Shengbiao
Jiang, Tao - Abstract:
- Abstract : FourL ‐rhamnose–benzoxazinone compounds as epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors were designed and synthesized. All structures of the compounds were characterized by 1 H‐NMR, 13 C‐NMR, and high‐resolutionmass spectrometry . The inhibition activities of the target compounds for the EGFR tyrosine kinase activity in vitro were determined. Compounds6a, 6b, 6c, 6d displayed moderate activity in targeting EGFR. Abstract :
- Is Part Of:
- Journal of heterocyclic chemistry. Volume 53:Number 5(2016:Sep.)
- Journal:
- Journal of heterocyclic chemistry
- Issue:
- Volume 53:Number 5(2016:Sep.)
- Issue Display:
- Volume 53, Issue 5 (2016)
- Year:
- 2016
- Volume:
- 53
- Issue:
- 5
- Issue Sort Value:
- 2016-0053-0005-0000
- Page Start:
- 1563
- Page End:
- 1569
- Publication Date:
- 2015-10-09
- Subjects:
- Heterocyclic compounds -- Periodicals
547.59 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/jhet.2463 ↗
- Languages:
- English
- ISSNs:
- 0022-152X
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 4998.200000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 2670.xml