Non-invasive monitoring of pulmonary artery pressure from timing information by EIT: experimental evaluation during induced hypoxia. (20th May 2016)

• Record Type: Journal Article
• Authors: Proença, Martin; Braun, Fabian; Solà, Josep; Adler, Andy; Lemay, Mathieu; Thiran, Jean-Philippe; Rimoldi, Stefano F
• Is Part Of: Physiological measurement. Volume 37:Number 6(2016:Jun.)
• Page Start: 713
• Page End: 726
• Publication Date: 2016-05-20
• Subjects: non-invasive -- pulmonary artery pressure -- pulmonary hypertension -- continuous monitoring -- electrical impedance tomography -- EIT -- PAP; Physiology -- Measurement -- Periodicals; Patient monitoring -- Periodicals; 612
• DOI: 10.1088/0967-3334/37/6/713
• Languages: English
• ISSNs: 0967-3334

Abstract

Abstract: Monitoring of pulmonary artery pressure (PAP) in pulmonary hypertensive patients is currently limited to invasive solutions. We investigate a novel non-invasive approach for continuous monitoring of PAP, based on electrical impedance tomography (EIT), a safe, low-cost and non-invasive imaging technology. EIT recordings were performed in three healthy subjects undergoing hypoxia-induced PAP variations. The pulmonary pulse arrival time (PAT), a timing parameter physiologically linked to the PAP, was automatically calculated from the EIT signals. Values were compared to systolic PAP values from Doppler echocardiography, and yielded strong correlation scores ( r = − 0.94 ± 0.07 ) for all three subjects. Results suggest the feasibility of non-invasive, unsupervised monitoring of PAP.