Dynamic ECG features for atrial fibrillation recognition. (November 2016)

• Record Type: Journal Article
• Authors: Abdul-Kadir, Nurul Ashikin; Mat Safri, Norlaili; Othman, Mohd Afzan
• Is Part Of: Computer methods and programs in biomedicine. Volume 136(2016)
• Page Start: 143
• Page End: 150
• Publication Date: 2016-11
• Subjects: Artificial neural network -- Atrial fibrillation -- Dynamic system -- k-fold cross validation -- Pattern recognition -- Support vector machine; Medicine -- Computer programs -- Periodicals; Biology -- Computer programs -- Periodicals; Computers -- Periodicals; Medicine -- Periodicals; Médecine -- Logiciels -- Périodiques; Biologie -- Logiciels -- Périodiques; Biology -- Computer programs; Medicine -- Computer programs; Periodicals; Electronic journals; 610.28
• DOI: 10.1016/j.cmpb.2016.08.021
• Languages: English
• ISSNs: 0169-2607

Abstract

Highlights: The characterization of atrial fibrillation using second order dynamic system. The appropriate windowing length for ECG signal processing during normal sinus rhythm and atrial fibrillation. The AF recognition used the pattern recognition machine learning methods (the ANN and SVM) with k-fold cross validation. The study proposed a method based on dynamic system, which achieved high accuracy of 95%. Our major results provide novel method in detection and classification of atrial fibrillation. Abstract: Background: Atrial fibrillation (AF) can cause the formation of blood clots in the heart. The clots may move to the brain and cause a stroke. Therefore, this study analyzed the ECG features of AF and normal sinus rhythm signals for AF recognition which were extracted by using a second-order dynamic system (SODS) concept. Objective: To find the appropriate windowing length for feature extraction based on SODS and to determine a machine learning method that could provide higher accuracy in recognizing AF. Method: ECG features were extracted based on a dynamic system (DS) that uses a second-order differential equation to describe the short-term behavior of ECG signals according to the natural frequency ( ω ), damping coefficient, ( ξ ), and forcing input ( u ). The extracted features were windowed into 2, 3, 4, 6, 8, and 10 second episodes to find the appropriate windowing size for AF signal processing. ANOVA and t-tests were used to determine the significant features. In addition, pattern recognition machine learning methods (an artificial neural network (ANN) and a support vector machine (SVM)) with k -fold cross validation ( k -CV) were used to develop the ECG recognition system. Results: Significant differences (p < 0.0001) were observed among all ECG groups (NSR, N, AF) using 2, 3, 4 and 6 second episodes for the features ω and u / ω ; 4, 6 and 8 second episodes for features ω and u ; 4 and 6 second episodes for features ω, u and u / ω, and; 10 second episodes for the feature ξ . The highest accuracy for AF recognition (AF, NSR) using ANN with k -CV was 95.3% using combination of features ( ω and u ; ω, u and u / ω ) and SVM with k -CV was 95.0% using a combination of features ω, u and u/ω. Conclusion: This study found that 4 s is the most appropriate windowing length, using two features ( ω and u ) for AF detection with an accuracy of 95.3%. Moreover, the pattern recognition learning machine uses an ANN with 10-fold cross validation based on DS.