Flow Cytometry: HD Flow Cytometry: An Improved Way to Quantify Cellular Interactions with Nanoparticles (Adv. Healthcare Mater. 18/2016). Issue 18 (21st September 2016)

• Record Type: Journal Article
• Authors: Selby, Laura I.; Kongkatigumjorn, Nachnicha; Such, Georgina K.; Johnston, Angus P. R.
• Is Part Of: Advanced healthcare materials. Volume 5:Issue 18(2016)
• Page Start: 2332
• Page End: 2332
• Publication Date: 2016-09-21
• Subjects: cell interactions -- deconvolution -- flow cytometry -- nanoparticles; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201670099
• Languages: English
• ISSNs: 2192-2640

Abstract

Abstract : Flow cytometry is used extensively to probe nanoparticle/cell interactions. However, distinguishing between weak nanoparticle fluorescence over cellular autofluorescence is challenging. L. Selby, A. Johnston and colleagues describe an algorithm that uses an iterative deconvolution process to identify the cells that have interacted with nanoparticles within the sample, allowing for the detection of small changes that would otherwise be missed, on page 2333.