Severe intravenous immunoglobulin‐induced hemolysis with pigment nephropathy managed with red cell exchange. Issue 5 (22nd August 2015)

• Record Type: Journal Article
• Authors: Lasica, Masa; Zantomio, Daniela
• Is Part Of: Journal of clinical apheresis. Volume 31:Issue 5(2016)
• Page Start: 464
• Page End: 466
• Publication Date: 2015-08-22
• Subjects: intravenous immune globulin (IVIg) -- acute renal failure -- ABO hemagglutinins; Hemapheresis -- Periodicals; Blood -- Transfusion -- Periodicals; Blood -- Transfusion, Autologous -- Periodicals; Cell separation -- Periodicals; Leukapheresis -- Periodicals; Plasmapheresis -- Periodicals; 615.39
• DOI: 10.1002/jca.21416
• Languages: English
• ISSNs: 0733-2459

Abstract

Abstract : We report on the use of red cell exchange in a case of severe intravenous immune globulin induced hemolysis and pigment nephropathy. Renal impairment and hemoglobinuria were not ameliorated by supportive measures including hydration. Partial red cell exchange with group O blood reduced hemoglobinuria and appeared to stabilize renal function. This is the first report on the use of red cell exchange in this clinical setting. J. Clin. Apheresis 31:464–466, 2016. © 2015 Wiley Periodicals, Inc.