Cover Picture: Transition‐Metal‐Free Decarboxylative Coupling Reactions for the Synthesis of Propargyl Alcohols (Asian J. Org. Chem. 9/2016). Issue 9 (8th September 2016)

• Record Type: Journal Article
• Authors: Irudayanathan, Francis Mariaraj; Kim, Jimin; Song, Kwang Ho; Lee, Sunwoo
• Is Part Of: Asian journal of organic chemistry. Volume 5:Issue 9(2016)
• Page Start: 1073
• Page End: 1073
• Publication Date: 2016-09-08
• Subjects: aldehydes -- alkynyl carboxylic acid -- decarboxylative coupling -- ketones -- propargyl alcohol; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.201600395
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract : Propargyl alcohols have been synthesized through a transition‐metal‐free decarboxylative coupling reaction . Aryl propiolic acids were treated with aldehyde (or ketone) in the presence of Cs2 CO3 to afford the corresponding propargyl alcohols in moderate‐to‐good yields. In particular, the reaction with 2, 2, 2‐trifluoroacetophenone afforded the trifluoromethylated propargyl alcohols in good yields. More information can be found in the full paper by S. Lee and co‐workers onpage 1148 in Issue 9, 2016 (DOI:10.1002/ajoc.201600265 ).