A Multifunctional Biomaterial with NIR Long Persistent Phosphorescence, Photothermal Response and Magnetism. Issue 18 (5th August 2016)

• Record Type: Journal Article
• Authors: Wu, Yiling; Li, Yang; Qin, Xixi; Qiu, Jianrong
• Is Part Of: Chemistry, an Asian journal. Volume 11:Issue 18(2016)
• Page Start: 2537
• Page End: 2541
• Publication Date: 2016-08-05
• Subjects: long persistent phosphors -- magnetism -- multifunctional -- photothermal response; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/asia.201600569
• Languages: English
• ISSNs: 1861-4728

Abstract

Abstract: There are many reports on long persistent phosphors (LPPs) applied in bioimaging. However, there are few reports on LPPs applied in photothermal therapy (PTT), and an integrated system with multiple functions of diagnosis and therapy. In this work, we fabricate effective multifunctional phosphors Zn3 Ga2 SnO8 : Cr 3+, Nd 3+, Gd 3+ with NIR persistent phosphorescence, photothermal response and magnetism. Such featured materials can act as NIR optical biolabels and magnetic resonance imaging (MRI) contrast agents for tracking the early cancer cells, but also as photothermal therapeutic agent for killing the cancer cells. This new multifunctional biomaterial is expected to open a new possibility of setting up an advanced imaging‐guided therapy system featuring a high resolution for bioimaging and low side effects for the photothermal ablation of tumors. Abstract : Multifunctional phosphors Zn3 Ga2 SnO8 : Cr 3+, Nd 3+, Gd 3+ with persistent NIR phosphorescence, photothermal response, and magnetism have been fabricated. These materials can act as NIR optical biolabels and magnetic resonance imaging (MRI) contrast agents for tracking early cancer cells, and also as a photothermal therapeutic agent for killing cancer cells.