Prediction of patient-specific post-operative outcomes of TAVI procedure: The impact of the positioning strategy on valve performance. Issue 12 (16th August 2016)

• Record Type: Journal Article
• Authors: Morganti, S.; Brambilla, N.; Petronio, A.S.; Reali, A.; Bedogni, F.; Auricchio, F.
• Is Part Of: Journal of biomechanics. Volume 49:Issue 12(2016)
• Page Start: 2513
• Page End: 2519
• Publication Date: 2016-08-16
• Subjects: TAVI -- Finite element analysis -- Patient-specific modeling; Animal mechanics -- Periodicals; Biomechanics -- Periodicals; Biomechanics -- Periodicals; Mécanique animale -- Périodiques; Biomécanique -- Périodiques; Electronic journals; 571.4305
• DOI: 10.1016/j.jbiomech.2015.10.048
• Languages: English
• ISSNs: 0021-9290

Abstract

Abstract: Prosthesis positioning in transcatheter aortic valve implantation procedures represents a crucial aspect for procedure success as demonstrated by many recent studies on this topic. Possible complications, device performance, and, consequently, also long-term durability are highly affected by the adopted prosthesis placement strategy. In the present work, we develop a computational finite element model able to predict device-specific and patient-specific replacement procedure outcomes, which may help medical operators to plan and choose the optimal implantation strategy. We focus in particular on the effects of prosthesis implantation depth and release angle. We start from a real clinical case undergoing Corevalve self-expanding device implantation. Our study confirms the crucial role of positioning in determining valve anchoring, replacement failure due to intra or para-valvular regurgitation, and post-operative device deformation.