A case of chromoblastomycosis by Fonsecaea nubica indicating a possible insect route of transmission. Issue 10 (22nd June 2016)

• Record Type: Journal Article
• Authors: Chen, Yingdan; Yin, Songchao; Li, Meirong; Chen, Rongzhang; Wei, Ling; Ma, Han; Deng, Shuwen; de Hoog, Gert Sybren; Lai, Wei; Lu, Chun; Feng, Peiying
• Is Part Of: Mycoses. Volume 59:Issue 10(2016)
• Page Start: 662
• Page End: 667
• Publication Date: 2016-06-22
• Subjects: Fonsecaea nubica -- chromoblastomycosis -- auricle -- internal transcribed spacer rDNA; Pathogenic fungi -- Periodicals; Medical mycology -- Periodicals; 616.969
• DOI: 10.1111/myc.12523
• Languages: English
• ISSNs: 0933-7407

Abstract

Summary: A first auricular case of chromoblastomycosis due to Fonsecaea nubica is reported in a 42‐year‐old Chinese male. He presented a slightly verrucous, erythematous plaque on his right auricle which had gradually extended over a 10‐year period, and the patient reported a history of dog flea sting before onset of the lesions. Diagnosis was based on histopathological and mycological examination of clinical samples, which revealed muriform cells. Identification of the aetiological agent was assessed by morphological characteristics and confirmed at species level by sequencing of the rDNA internal transcribed spacer (ITS). The patient showed marked clinical improvement after 3 months combination therapy with itraconazole and terbinafine. The possible mode of transmission of auricular chromoblastomycosis is discussed.