Biomarkers in Pediatric Cardiac Critical Care. (August 2016)

• Record Type: Journal Article
• Authors: Domico, Michele; Allen, Meredith
• Is Part Of: Pediatric critical care medicine. Volume 17(2016)Supplement 1 8
• Publication Date: 2016-08
• Subjects: biomarkers -- monitoring -- myocardial injury -- outcomes -- pediatrics; Pediatric intensive care -- Periodicals; Pediatric emergencies -- Periodicals; 618.05
• DOI: 10.1097/PCC.0000000000000778
• Languages: English
• ISSNs: 1529-7535

Abstract

Abstract : Objectives: In this review, we discuss the physiology, pathophysiology, and clinical role of troponin, lactate, and B-type natriuretic peptide in the assessment and management of children with critical cardiac disease. Data Source: MEDLINE, PubMed. Conclusion: Lactate, troponin, and B-type natriuretic peptide continue to be valuable biomarkers in the assessment and management of critically ill children with cardiac disease. However, the use of these markers as a single measurement is handicapped by the wide variety of clinical scenarios in which they may be increased. The overall trend may be more useful than any single level with a persistent or rising value of more importance than an elevated initial value.