ChemInform Abstract: Rh‐Catalyzed Reductive Mannich‐Type Reaction and Its Application Towards the Synthesis of (.+‐.)‐Ezetimibe. Issue 40 (September 2016)

• Record Type: Journal Article
• Authors: Isoda, Motoyuki; Sato, Kazuyuki; Kunugi, Yurika; Tokonishi, Satsuki; Tarui, Atsushi; Omote, Masaaki; Minami, Hideki; Ando, Akira
• Is Part Of: ChemInform. Volume 47:Issue 40(2016)
• Page Start: no
• Page End: no
• Publication Date: 2016-09
• Subjects: azetidine derivatives -- ring closure reactions, annulation reactions -- catalysis, phase‐transfer catalysis -- aminomethylation; Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201640096
• Languages: English
• ISSNs: 0931-7597

Abstract

Abstract: The protocol is applied to the synthesis of (.+‐.)‐ezetimibe (VIII), a potent β‐lactamic cholesterol absorption inhibitor.