A H+-triggered bubble-generating nanosystem for killing cancer cells. Issue 72 (4th August 2016)
- Record Type:
- Journal Article
- Title:
- A H+-triggered bubble-generating nanosystem for killing cancer cells. Issue 72 (4th August 2016)
- Main Title:
- A H+-triggered bubble-generating nanosystem for killing cancer cells
- Authors:
- Yang, Lili
Wen, Zuhuang
Long, Yijuan
Huang, Ning
Cheng, Yuan
Zhao, Li
Zheng, Huzhi - Abstract:
- Abstract : A bubble-generating nanosystem can kill cancer cells by the quick release of CO2 bubbles. Abstract : We constructed a H + -triggered bubble-generating nanosystem (BGNS), which generated CO2 bubbles in the acidic environment of lysosomes after being internalized by cancer cells. The quickly generated bubbles caused enhanced lysosomal membrane permeabilization. As expected, H + -triggered BGNS possessed remarkable cytotoxicity against MCF-7 breast cancer cells, and successfully overcame the multidrug resistance of MCF-7/ADR cells.
- Is Part Of:
- Chemical communications. Volume 52:Issue 72(2016)
- Journal:
- Chemical communications
- Issue:
- Volume 52:Issue 72(2016)
- Issue Display:
- Volume 52, Issue 72 (2016)
- Year:
- 2016
- Volume:
- 52
- Issue:
- 72
- Issue Sort Value:
- 2016-0052-0072-0000
- Page Start:
- 10838
- Page End:
- 10841
- Publication Date:
- 2016-08-04
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c6cc04511a ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 1836.xml