A New Rhodamine B‐based Fluorescent Probe for pH Detection and Bioimaging under Strong Acidic Conditions. (7th September 2016)

• Record Type: Journal Article
• Authors: Yang, Quan; Zou, Jingrong; Chirumarry, Sridhar; Huo, Chang; Tang, Linlin; Zhang, Fang; Xiang, Yi; Zuo, Hua; Shin, Dong‐Soo; Peng, Xiang
• Is Part Of: Bulletin of the Korean Chemical Society. Volume 37:Number 9(2016)
• Page Start: 1453
• Page End: 1457
• Publication Date: 2016-09-07
• Subjects: pH‐sensitive probe -- Rhodamine B derivative -- Fluorescence -- Bioimaging -- Acidic condition; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/bkcs.10888
• Languages: English
• ISSNs: 0253-2964

Abstract

Abstract : A new pH‐sensitive rhodamine derivative was designed and synthesized using coupling reaction of rhodamine hydrazine with commercially available 3‐bromo‐4‐hydroxybenzaldehyde, and characterized via NMR, HRMS, UV and fluorescent spectra. The obtained probe was marked with yellow fluorescence under neutral condition and pink in strongly acidic media. It has high quantum yields, is not susceptible to metal interference, and has high penetration ability for cell membrane and also further applicable in bioimaging. Abstract :