Anisotropically Stiff 3D Micropillar Niche Induces Extraordinary Cell Alignment and Elongation. Issue 15 (18th May 2016)
- Record Type:
- Journal Article
- Title:
- Anisotropically Stiff 3D Micropillar Niche Induces Extraordinary Cell Alignment and Elongation. Issue 15 (18th May 2016)
- Main Title:
- Anisotropically Stiff 3D Micropillar Niche Induces Extraordinary Cell Alignment and Elongation
- Authors:
- Alapan, Yunus
Younesi, Mousa
Akkus, Ozan
Gurkan, Umut A. - Abstract:
- Abstract : A microfabricated pillar substrate is developed to confine, align, and elongate cells, allowing decoupled analysis of stiffness and directionality in 3D. Mesenchymal stem cells and cardiomyocytes are successfully confined in a 3D environment with precisely tunable stiffness anisotropy. It is discovered that anisotropically stiff micropillar substrates provide cellular confinement in 3D, aligning cells in the stiffer direction with extraordinary elongation.
- Is Part Of:
- Advanced healthcare materials. Volume 5:Issue 15(2016)
- Journal:
- Advanced healthcare materials
- Issue:
- Volume 5:Issue 15(2016)
- Issue Display:
- Volume 5, Issue 15 (2016)
- Year:
- 2016
- Volume:
- 5
- Issue:
- 15
- Issue Sort Value:
- 2016-0005-0015-0000
- Page Start:
- 1884
- Page End:
- 1892
- Publication Date:
- 2016-05-18
- Subjects:
- 3D microenvironment -- cell shape -- microfabrication -- micropillar arrays -- stiffness anisotropy
Biomedical materials -- Periodicals
610.28 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2192-2659 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1002/adhm.201600096 ↗
- Languages:
- English
- ISSNs:
- 2192-2640
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0696.854650
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 2336.xml