Application of post-genomic techniques in dog cancer research. Issue 9 (27th June 2016)

• Record Type: Journal Article
• Authors: Ceciliani, F.; Roccabianca, P.; Giudice, C.; Lecchi, C.
• Is Part Of: Molecular bioSystems. Volume 12:Issue 9(2016:Sep.)
• Page Start: 2665
• Page End: 2679
• Publication Date: 2016-06-27
• Subjects: Molecular biology -- Periodicals; Biochemistry -- Periodicals; 571.7405
• DOI: 10.1039/c6mb00227g
• Languages: English
• ISSNs: 1742-206X

Abstract

Abstract : We present in this review the most recent achievement in the application of transcriptomics, proteomics and metabolomics to canine cancer research. The protocols to recover material suitable for omics analyses from formalin-fixed, paraffin-embedded tissues are highlighted, together with the potential of omics in veterinary cancer diagnostics. Abstract : Omics techniques have been widely applied to veterinary science, although mostly on farm animal productions and infectious diseases. In canine oncology, on the contrary, the use of omics methodologies is still far behind. This review presents the most recent achievement in the application of postgenomic techniques, such as transcriptomics, proteomics, and metabolomics, to canine cancer research. The protocols to recover material suitable for omics analyses from formalin-fixed, paraffin-embedded tissues are presented, and omics applications for biomarker discovery and their potential for cancer diagnostics in veterinary medicine are highlighted.